Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain원숭이와 생쥐의 비교 miRNA 전사체는 MYOC가 뇌로의 크립토코커스 네오포르만스 침입에 대한 억제제임을 보여줍니다Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] 유전자 메커니즘, [키워드] AIDS Brain brain dissemination brains C. neoforman C. neoformans caused Central nervous system centric clinical samples clinically CNS Comparative Cryptococcal meningoencephalitis cryptococcosis Cryptococcus neoforman Cryptococcus neoformans cytoskeleton dissemination enhancer facilitate fungal Fungal infection help HIV/AIDS HIV/AIDS patient HIV/AIDS patients host-pathogen interactions hosts human pathogen Immune cell immune cells individuals Infection inhibitor inhibitors Invasion macaque Macrophage mechanism meningoencephalitis mice miRNA miRNA transcriptome. MYOC myocilin Pathogenic microorganisms pathway Patient patients with COVID-19 performed Prevalence regulated response reveal Transcriptome transcriptomics Trojan horse [DOI] 10.1080/22221751.2022.2081619 PMC 바로가기 [Article Type] Article
Fungal colonization and infections in patients with COVID-19 in intensive care units: A real-life experience at a tertiary-care hospitalResearch article Published on 2022-11-012022-10-05 Journal: Respiratory medicine and research [Category] 진단, [키워드] age antifungal therapy Antifungal treatment Candida albican Candida albicans Computed tomography COVID-19 COVID-19 diagnosis COVID-19-associated pulmonary aspergillosis cross-contamination diagnostic evaluate exhibited Fatality rate fungal Fungal colonization Fungal infection highlight hospital ICU ICUs Infection intensive care intensive care unit Invasive mechanical ventilation laboratory data management mechanical ventilation medical records men outcome pandemic Patient patients patients with COVID-19 performed problem Result risk Risk factors the patient Thorax women [DOI] 10.1016/j.resmer.2022.100937 [Article Type] Research article
The TLR-NF-kB axis contributes to the monocytic inflammatory response against a virulent strain of Lichtheimia corymbifera, a causative agent of invasive mucormycosisArticle Published on 2022-10-132022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] 24 hours activated Activation Apoptosis apoptotic cascade caused Cell cell damage characterized contribute COVID-19 CTLs Cytokines Diabetes Mellitus Diagnosis Diseases ENhance exhibit fungal Fungal infection fungi Hematological malignancies host cell Host immune response host inflammatory response host-pathogen interactions human monocyte human monocytes IL-1β IL-6 increase in individual Infection Inflammatory Inflammatory response inflammatory signaling Interaction invasive killing life-threatening modulation monocyte mortality rate Mucorales Mucormycosis NF-kB Occurrence organ pathogenic phagocyte phagocytosis priming pro-inflammatory cytokine produced progression PRRs receptor receptors receptors. regulate secreted signaling pathway spore susceptible synergistic therapy TLR TLR4 TLRs TNF-α Toll-like receptor transcription factor virulent [DOI] 10.3389/fimmu.2022.882921 PMC 바로가기
Black Fungus and beyond: COVID-19 associated infectionsReview article Published on 2022-10-012022-10-05 Journal: Clinical imaging [Category] COVID19(2023년), SARS, 바이오마커, 진단, 치료기술, [키워드] Bacterial black changes in clinical manifestation Clinical outcome Co-infection Complication consolidation COVID-19 COVID-19 infection COVID-19 patient deviation differential diagnosis expected fungal fungus hospitalized COVID-19 patient Infection infections Inflammatory opportunistic infection outcome Patient patient population physician radiologic reported Superimposed infection thrombotic while worsening [DOI] 10.1016/j.clinimag.2022.07.005 [Article Type] Review article
CT findings of COVID-19-associated pulmonary aspergillosis: a systematic review and individual patient data analysisResearch article Published on 2022-10-012022-10-05 Journal: Clinical imaging [Category] 바이오마커, 진단, [키워드] Abnormalities abnormality accompany age Analysis aspergillosis Atypical authors collected common conducted consolidation Coronavirus 2019 COVID-19 CT finding eight fungal Ground-glass opacities identify nodules Patient patient data Pneumonia reported Result systematic literature search systematic review tomography X-ray computed [DOI] 10.1016/j.clinimag.2022.07.003 [Article Type] Research article
The first detection of Pneumocystis jirovecii in asthmatic patients post-COVID-19 in JordanArticle Published on 2022-09-162022-11-15 Journal: Bosnian Journal of Basic Medical Sciences [Category] SARS, 치료기술, 치료제, [키워드] Asthma asthma patient asthmatic patient caused chronic lung disease Cohort coronavirus disease Corticosteroid COVID-19 detect determine DHFR differential diagnosis Efficiency evaluate fungal HIV Human immunodeficiency virus Immunocompromised patients Immunosuppression Infection Jordan maintain Nasopharyngeal swab occur Patient patients Pneumonia polymerase chain positive qPCR qPCR assay Quantitative real time risk factor SARS-CoV-2 Sputum sample sputum samples TaqMan target tested the mean treated were used [DOI] 10.17305/bjbms.2022.7335 PMC 바로가기
Viral cross-class transmission results in disease of a phytopathogenic fungus Research Published on 2022-08-312022-10-05 Journal: The ISME Journal [Category] 유전자 메커니즘, [키워드] Asymptomatic B. cinerea Botrytis cinerea Brassica carried change characterized Contact Cross-species transmission described disease dsRNA Efficiency fungal fungi groups growth Implications Infection isolate mycelial no significant difference occur pathogen pathogenicity phenotypical plant provide RNA RNA sequencing spore Strains Transmission transmitted vectors virus virus [DOI] 10.1038/s41396-022-01310-y [Article Type] Research
Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data setObservational Study Published on 2022-08-032022-10-05 Journal: Critical Care [Category] 임상, [키워드] Adjusting Admission admitted to ICU Analysis antibiotic use Antibiotics Bacterial Co-infection Cohort collected confounder continuous variable Corticosteroid corticosteroid therapy Corticosteroids COVID-19 COVID-19 pandemic COVID-19 patients Critical care Critically ill develop Duration First wave fungal greater heterogenous ICU ICU admission ICUs incident Infection infections intensive care International involved Mann-Whitney U test multi-drug resistant multicenter organism pandemic Patient patients PCR-confirmed COVID-19 diagnosis Pearson Pneumonia Propensity score receiving Registered severe COVID-19 significantly steroid subsequent suggested Surveillance Univariate analysis use of corticosteroid use of corticosteroids variable [DOI] 10.1186/s13054-022-04108-8 PMC 바로가기 [Article Type] Observational Study
Intraventricular CNS aspergillosis in a patient with prior history of COVID-19: Case report and review of literatureCase report Published on 2022-08-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 진단, [키워드] administration approach aspergillosis Case report cause CNS Co-infection Computerized tomography Confusion COVID-19 COVID-19 infection COVID-19 patient differential diagnosis discharged dissemination edema fungal fungal disease hospital immune dysfunction Immunocompromised patients include Infection intravenous intraventricular Intraventricular space invasive Loss of consciousness magnetic resonance imaging majority medications MRI Mucormycosis neurologic Patient poor prognosis SARS-CoV-2 Severe COVID-19 Infection surgical resection Symptom thought transcortical treated Treatment with COVID-19 [DOI] 10.1016/j.amsu.2022.104122 [Article Type] Case report
COVID-19 and Fungal Infections: A Double DebacleMini review Published on 2022-08-012022-10-05 Journal: Microbes and infection [Category] SARS, 바이오마커, 진단, 치료기술, [키워드] anti-inflammatory therapies Aspergillus Better Candida Co-infection co-occurrence COVID-19 COVID-19 patient COVID-19 patients Critically ill Diagnosis diagnostic tests fungal Fungal infection healthcare highlight highlighting Immunosuppressant Immunosuppression Infection Infectious disease Interaction management Mucorale patients Risk factors SARS-CoV-2 Taking treatable Treatment [DOI] 10.1016/j.micinf.2022.105039 [Article Type] Mini review